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TOP >  学術論文:マスティハ  もくじ > マスティハ精油の抗菌効果

 


1.   Planta Medica, Volume 65, Issue 8, December 1999, Pages 749-752       
  Chemical composition and antimicrobial activity of the essential oils of Pistacia lentiscus var. chia     
  Magiatis, P; Melliou, E; Skaltsounis, A L; Chinou, I B; Mitaku, S  
  University Of Athens, Department of Pharmacy - Division Of Pharmacognosy, Panepistimioupolis Zografou Athens, Greece  
  Abstract
The chemical composition of the three essential oils obtained by steam distillation of the mastic gum, leaves and twigs of Pistacia lentiscus var. chia, was studied by GC/MS. Sixty nine constituents were identified from the oils. alpha-Pinene, myrcene, trans-caryophyllene and germacrene D were found to be the major components. The in vitro antimicrobial activity of the three essential oils and of the resin (total, acid and neutral fraction) against six bacteria and three fungi is reported.
 


2.   International Biodeterioration & Biodegradation, Volume 36, Issues 3-4, October-December 1995,
Pages 411-420
 
  Antimicrobial Activity of the Essential Oil of Mastic Gum (Pistacia lentiscus var. chia) on Gram Positive and Gram Negative Bacteria in Broth and in Model Food System  
  Chrysoula C. Tassoua, * and G. J. E. Nychasb  
  a National Agricultural Research Foundation, Institute of Technology of Agricultural Products, S. Venizelou 1, Lycovrisi 14123 Athens Greece
b Agricultural University of Athens, Department of Science of Food and Agricultural Industries, Laboratory of Food Microbiology and Biotechnology, Iera Odos 75 Athens 11855 Greece
 
  Abstract
The addition of mastic gum in broth culture inoculated with Staphylococcus aureus, Lactobacillus plantarum, Pseudomonas fragi and Salmonella enteritidis inhibited the growth of these organisms as monitored with the Malthus Instrument (in microsiemens). The rate of inhibition was greater on Gram positive bacteria than that observed on Gram negative bacteria. In most cases the size of inoculum and the concentration of mastic gum affected the growth/survival of the organisms. The addition of EDTA in coliform broth increased the inhibitory activity of mastic gum against Salmonella enteritidis, but did not affect significantly the inhibition of this organism in Model Food System (skim milk) at 37°C.
 


3.     Journal of Chemotherapy Vol. 8, 1996, Pages 207-209  
  In vitro antimicrobial activity of Pistacia lentiscus L. extracts  
  Iauk L, Ragusa S, Rapisarda A, Franco S, Nicolosi VM.  
 
Abstract
The in vitro antimicrobial activity of Pistacia lentiscus L. extracts was determined. Pistacia lentiscus L. extracts were tested on bacteria (Sarcina lutea, Staphylococcus auereus, and Escherichia coli) and Fungi (Candiada albicans, Cadida parapsilosis, Torulopsis glabrata and Cryptococcus neoformans). Of the different plant extractions, decoctions showed the best antibacterial activity, but the activity against fungal cells appears to be much more interesting
 
     

4.    International Journal of Food Microbiology Vol. 94 2004, Pages 313-22  
  Effects of mastic resin and its essential oil on the growth of proteolytic Clostridium botulinum  
  Daphne Phillips Daifasa, James P. Smit, a, Burke Blanchfieldb, Greg Sandersb, John W. Austinb and John Koukoutisisc  
  a Department of Food Science and Agricultural Chemistry, McGill University, Macdonald Campus, 21,111 Lakeshore Road, St. Anne de Bellevue, Quebec, Canada H9X 3V9
b Bureau of Microbial Hazards, Food Directorate, Health Products and Food Branch, Health Canada, Ottawa, Ontario, Canada K1A 0L2
c Collège d'Alfred, Université de Guelph, 31, rue St-Paul, C.P. 580, Alfred, Ontario, Canada K0B 1A0
 
  Abstract
Studies were done to determine the effect of mastic resin and its essential oil, alone and in conjunction with ethanol, on the growth of proteolytic strains of Clostridium botulinum in media, and on neurotoxin production in challenge studies with English-style crumpets. Preliminary studies, using a spot-on-the-lawn method, indicated that high levels of mastic resin in ethanol (~8% w/w) were required for complete inhibition of all strains of C. botulinum tested, but mastic resin in ethanol had a greater anti-botulinal effect than ethanol alone. However, only low levels of mastic oil (~0.3% v/v) were required for inhibition of proteolytic strains of C. botulinum. Both studies showed a strain specific inhibition, with C. botulinum type A strains being more sensitive to mastic resin and its essential oil than type B strains. However, mastic resin in ethanol proved to be more effective when used as a vapor phase inhibitor applied to cotton pads and placed inside inoculated plates than when added directly to media. While both mastic resin and its essential oil inhibited the growth of proteolytic strains of C. botulinum in vitro, they failed to inhibit neurotoxin production in challenge studies with C. botulinum in English-style crumpets.
Author Keywords: Mastic; Ethanol; Clostridium botulinum; Botulinum neurotoxin
 


5.    Epitheorese Klinikes Farmakologias kai Farmakokinetikes, International Edition. 2001 16: 199-201.  
  The Antibacterial and antifungal Action of the Chios Mastic Essential Oil.  
  E.E Protopapa, V Spiliotis, V. Kefala, A. Triantafyllou, J Tsaknis.  
  Technological Educational Institution, Athens & Laboratory og Biologikal Chemistry, University of Athens Medical School.  
  Abstract
The effect of Chios mastic essential oil on the growth of nine bacteria (m. Luteus, S. epidermis, B. subtilis, S. aureus, E. Coli, S. Mutans, V. alcalencens, V. parulla and l. casei) and three fungi ( C. albicans, A. maelundi and A. odontolyticus) was tested in cultures in a minimal concentration inhibition assay. Bacteriostatic effects were observed on M. Luteus, S. epidermis, B. Subtilis, S. Aureus, E. Coli, and V. alcalencens and antifungal effects on C. albicans and A. maelundi. The bacteriostatic and antifungal effects of the mastic oil on A. maelundi and V. alcalencens, respectively, microorganisms which are present in the mouth flora, could be correlated with the observed effects of mastic chewing gum on reducing dental plaques and mouth infections.
 


6.    Epitheorese Klinikes Farmakologias kai Farmakokinetikes, International Edition. 2001 16: 203-205.  
  The Antiphlogistic Action of the Chios Mastic Essential Oil: Treatment of Skin Irritations Resulting from Hair Epilation and peeling with lotions Containing Mastic Essential Oil.  
  E.E Protopapa, A. Heliou, A. Tsigonia, V. Kefala, A. Triantafyllou, J Tsaknis.  
  Technological Educational Institution, Athens, Technological Educational Institution, of Thessaloniki & Laboratory of Biologikal Chemistry, University of Athens Medical School.  
  Abstract
The antiphlogistic effect of mastic essential oil was tested in skin subjected to epilation either by thermolysis or enzymes in different skin region and peeling. Creams containing mastic essential oil significantly reduced the time period necessary to relieve the irritatiom resulting from epilation or peeling, compared to skin regions treated with placebo cream devoid of the mastic oil.
 


7.    Pharmaceuticals 2009 pages 2-10 マスティハ精油の抗菌効果_マスティック
  Fractionation of Mastic Gum in Relation to Antimicrobial Activity  
  Mohammad Sharif Sharifi 1,* and Stuart Loyd Hazell 2  
  1 School of Medicine, University of Western Sydney, Australia
2 Faculty of Sciences, University of Queensland, Australia
 
  Abstract
Mastic gum is a viscous light-green liquid obtained from the bark of Pistacia lentiscus var. chia. which belongs to the Anacardiaceae family. The gum has been fractionated to investigate the antimicrobial activity of the whole gum and its fractions against various strains of Helicobacter pylori. The polymeric gum fraction was separated from the essential oil and the resin (trunk exudates without essential oil) to assess and compare the anti-H. pylori activity of the polymer fraction against lower molecular weight fractions, the gum itself and masticated gum. The polymer fraction was also oxidized and assessed for antimicrobial activity.
Keywords: Mastic Gum; Helicobacter pylori; Pistachia lentiscus.
 




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